Detailed APPSC Civil Assistant Surgeons in Preventive Exam Syllabus

Title: Detailed APPSC Civil Assistant Surgeons in Preventive Examination Syllabus

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Name of Organisation	Andhra Pradesh Public Service Commission
Name of Posts	Civil Assistant Surgeons in Preventive
Official Website	https://psc.ap.gov.in
Recruitment Details	Andhra Pradesh Public Service Commission Civil Assistant Surgeons in Preventive
Type of Test	Objective Type
Test Mode	Online (Computer Based Test – CBT)

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Detailed APPSC Civil Assistant Surgeons in Preventive Examination Exam Pattern

PART-A: WRITTEN (OBJECTIVE TYPE) EXAMINATION

Paper-1	General Studies & Mental Ability (Degree standard)	150 Marks	150 Minutes	150 Questions
Paper-2	Concerned Optional subject (P.G. Standard) i.e., Micro Biology OR Pathology OR Bio-Chemistry OR Transfusion Medicine	300 Marks	150 Minutes	150 Questions

PART-B: INTERVIEW 50 Marks

Detailed APPSC Civil Assistant Surgeons in Preventive Examination Syllabus

PAPER-1.: GENERAL STUDIES AND MENTAL ABILITY

1. General Science – Contemporary developments in Science and Technology and their implications including matters of every day observation and experience, as may be expected of a well-educated person who has not made a special study of any scientific discipline.

2. Current events of national and international importance.

3. History of India – emphasis will be on broad general understanding of the subject in its social, economic, cultural and political aspects with a focus on AP Indian National Movement.

4. World Geography and Geography of India with a focus on AP.

5. Indian polity and Economy – including the country’s political system- rural development – Planning and economic reforms in India.

6. Mental ability reasoning and inferences

TRANSFUSION MEDICINE

1) BLOOD DONATION AND COLLECTION:
a) Donor selection and Blood collection
b) Autologous Blood donation and Transfusion
c) Apheresis

2) IMMUNOLOGIC AND GENETIC PRINCIPLES
a) Molecular Biology in Transfusion Medicine
b) Blood group genetics
c) Immunology

3) SEROLOGIC PRINCIPLES AND TRANSFUSION MEDICINE
a) Pretransfusion testing
b) Initial detection and Identification of Allo Antibodies to Red cell antigens
c) Positive Direct anti globulins Test and Immune medicated Red cell destruction

4) CLINICAL CONSIDERATIONS IN TRANSFUSION PRACTICE
a) Blood Transfusion Practice
b) Administration of Blood and components
c) Prenatal issues in Transfusion practice

5) Qualify control of blood and blood components reagents and kits – external and internal qualify control
6) Bio-safety
7) Blood utilization management
8) Transportation and shipment dangerous goods
9) Red cell typing
10) Adsorption and elution technique
11) Haemolytic anaemias
12) Haemolytic disease of the fetus and new born

MICROBIOLOGY

General Microbiology

1. Organization of Clinical Microbiology Lab & quality assurance
2. Microscopy and staining methods
3. Automation in Microbiology
4. Biomedical waste management and safety in Microbiology
5. Basic equipment used Microbiology lab and its maintenance
6. Laboratory strategy in the diagnosis of infective syndromes
7. Disease surveillance and outbreak investigation
8. National Programmes in disease control and their implementation
9. Specimen collection, culture methods, identification and storage of bacteria
10. Laboratory control of antimicrobial therapy and mechanism of action of antibiotics
11. Bacterial genetics and recombinant DNA technology 12. Nucleic acid techniques in diagnostic Microbiology
13. Molecular Epidemiology of infectious agents – significance and methods
14. Management of Experimental animals
15. Examination of water, milk, food and air
16. Sterilization and disinfection

Immunology

I. Concept of self and non-self recognition
1. Need for self recognition
2. Antigens and Receptors

II. The Innate Immune System
1. Barriers to infection
2. Cells of the Innate Immune system
3. Innate Immune function

III. The Adaptive Immune system
1. Cells and Organs of adaptive immunity
2. Molecules of adaptive immunity
3. Generation of Immune diversity
4. Lymphocyte development, activation and function
5. Regulation of adaptive responses

IV. Clinical aspects of Immunity
1. Hypersensitivity reactions
2. Immune deficiency
3. Autoimmunity
4. Transplantation
5. Immune Pharmacotherapy
6. Tumor Immunity
7. Measurement of Immune function – Antigen antibody reactions

Parasitology

I. General Parasitology
1. Taxonomy
2. Morphology, life cycle & Epidemiology
3. Immunity and Pathogenesis of Parasitic infections
4. Laboratory diagnosis of parasitic infections

II. Protozoa
1. Amoebae
2. Intestinal, oral and genital flagellates – Giardia, Trichomonas
3. Blood and Tissue flagellates – Leishmania, Trypanosomes
4. Malaria parasites and Piroplasms

III. Helminths
1. Pseudophyllidean Tape worms – Diphyllobothrium, Spirometra
2. Cyclophyllidean Tape worms – Taenia, Echinococcus, Hymenolepis, Dypylidium
3. Trematodes – Schistosomes
4. Trematodes – Fasciola, Echniostoma, Dicrocoelium, Paragoniums, Clonorchis, Ophisthorchis, Heterophyes
5. Nematodes – Apharid – Trichinella, Trichuris, Capillaria, Strongyloides
6. Burrata Nematodes – Hookworm, Trichostrongylus, Angiostrongylus, Enerobius, Ascaris
7. Filarial Nematodes – Wuchereria, Brugia, Onchocerca, Loa loa, Manronella, Dirofilaria
8. Spirurid Nematodes – Drancunculus, Gnathostoms 9. Ectoparasites – Mosquito, Sandfly, Tick, Mite, Cyclops, Louse

Systemic Bacteriology
1. Staphylococcus: Cluster-forming Gram positive Cocci
2. Streptococcus and Enterococcus
3. Streptococcus pneumoniae
4. Neisseria, Moraxella, Acinetobacter
5. Corynebacterim

Virology

1. The nature of viruses
2. Classification of viruses
3. Morphology: virus structure
4. Virus replication
5. The genetics of viruses

Mycology
1. The morphology and reproduction in fungi
2. Classification of fungi
3. Contaminant and opportunistic fungi
4. Fungi causing superficial mycoses
5. Fungi causing subcutaneous mycoses

BIOCHEMISTRY

1. Introduction to Biochemistry
2. Cell Molecular and Functional Organisation
3. Chemistry of Carbohydrates
4. Chemistry of Lipids
5. Proteins
6. Nucleic Acids
7. Enzymes
8. Biological Oxidation
9. Vitamins
10. Carbohydrate Metabolism
11. Metabolism of Proteins
12. Metabolism of Nucleic acids
13. Lipid Metabolism
14. Haemoglobin structure, function and Metabolism, Porphyrias and Hemoglobinopathies
15. Integration of Metabolism
16. Mineral metabolism
17. Nutrition
18. Detoxification
19. Hormones
20. Function Tests
21. Fluid Electrolyte and Acid base balance
22. Plasma proteins and immunoglobulin
23. Biological membrane
24. Carcinogenesis and malignancy

CLINICAL CHEMISTRY

LABORATORY PRINCIPLES
1. GENERAL LABORATORY TECHNIQUES, PROCEDURES AND SAFETY
2. SPECIMEN COLLECTION AND OTHER PRE-ANALYTICAL VARIABLES

ANALYTICAL TECHNIQUES AND INSTRUMENTATION

1. SPECTROPHOTOMETRIC TECHNIQUES
2. BASIC PRINCIPLES OF RADIO ACTIVITY AND ITS MEASUREMENT
3. ELECTOCHEMISTRY
4. ELECTROPHORESIS
5. CHROMATOGRAPHY/ MASS SPECTOMETRY
6. PRINCIPLES OF CLINICAL ENZYMOLOGY
7. PRINCIPLES OF IMMUNOCHEMICAL TECHNIQUES
8. NUCLEIC ACID TECHNIQUES
9. AUTOMATION IN CLINICAL LABORATORY

LABORATORY OPERATIONS

1. Evaluation of Methods with an introduction to statistical techniques
2. Establishment and use of reference values
3. Clinical laboratory informatics
4. Laboratory Management
5. Quality Management

ANALYTES

ORGAN FUNCTION TESTS

PREGNANCY

INHERITED DISEASES

PATHOLOGY

CELLULAR ADAPTATIONS
CELLULAR EVENTS
TISSUE RENEWAL & REPAIR
BLOOD VESSELS
THE HEART
RED BLOOD CELLS & BLEEDING DISORDERS
LYMPH NODES
THE LUNG
HEAD & NECK
GASTROINTESTINAL TRAIT
LIVER
KIDNEY
POWER URINARY TRACK MALE GENITAL SYSTEM
FEMALE GENITAL SYSTEM
THE BREAST
ENDOCRINE SYSTEM
SKIN
BONES JOINTS & SOFT
CNS

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